Whispering Gallery Mode Biosensor
نویسندگان
چکیده
sensor which uses whispering gallery modes (WGMs) in dielectric microspheres for biomolecular detection. The WGMs are excited by evanescent coupling to an etch-eroded single mode optical fiber. WGM resonance positions are detected as Lorentzian dips in the intensity of the fiber-transmitted light. The polarization of molecules interacting with the evanescent field of the WGM on the microsphere surface leads to a red shift of a given WGM resonance wavelength. Chemical modification of the sensor surface allows specific detection of proteins, DNA and (nano-)particles such as viruses and bacteria.
منابع مشابه
Ultra-Sensitive Optical Biosensor Based on Whispering Gallery Modes: The Effect of Buffer Solutions Refractive Index on Their Sensitivity and Performance
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A finite element analysis is made of the shifts of resonance frequencies of whispering-gallery-mode (WGM) for a fiber-microsphere coupling miniature sensor. The timedomain Maxwell’s equations were adopted to describe the near-field radiation and solved by the Inplane TE waves application mode of the FEMLAB. The electromagnetic field as well as the radiation energy distribution can be easily obt...
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